"The Birdman of Djiizari" from Challengers of the Unknown vol.1 #5 (DC, 1958) by Jack Kirby and Wally Wood
I always think of Jack Kirby when I think of the Challengers of the Unknown, despite the fact he only drew the first dozen issues of its 75 ish run, but that's the power of the King! Only a couple years later, he would go on to co-create the Fantastic Four with Stan Lee, which certainly look like they're BASED on the Challs. Rocky the strongman (come on!), Red the hotshot, Prof the scientist, June the girl... Only Ace doesn't really get an FF analog, folded as he is into Ben Grimm. The FF are the Challs if the accident that brought them together working on "borrowed time" had given them powers.